2025 Cruises out of San Diego, California

There are 40 cruises that depart from San Diego, CA in the year 2025. Only one cruise line offers cruises that leave out of San Diego in 2025 - Holland America (total of 40 sailings, among them 20 on Nieuw Amsterdam, 14 on Zaandam and 4 on Koningsdam).

You can see San Diego cruise schedule for 2025 in the table below. Be sure to look at the $/Day column to find cheap San Diego cruise deals in 2025.

March 22

From

$1,299

$/Day:

$186

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Koningsdam

Itinerary:

San Diego Round Trip

Select

March 22

From

$1,499

$/Day:

$136

Duration:

11 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

March 29

From

$699

$/Day:

$100

Duration:

7 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Koningsdam

Itinerary:

San Diego to Vancouver

Select

April 2

From

$1,299

$/Day:

$130

Duration:

10 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

April 12

From

$1,804

$/Day:

$129

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

April 12

From

$1,199

$/Day:

$171

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

April 19

From

$1,099

$/Day:

$157

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

April 26

From

$899

$/Day:

$82

Duration:

11 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

Vancouver

Ship:

Zaandam

Itinerary:

San Diego to Vancouver

Select

April 26

From

$1,099

$/Day:

$157

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

April 26

From

$479

$/Day:

$80

Duration:

6 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Eurodam

Itinerary:

San Diego to Vancouver

Select

April 30

From

$389

$/Day:

$97

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Nieuw Amsterdam

Itinerary:

San Diego to Vancouver

Select

May 3

From

$299

$/Day:

$75

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

Vancouver

Ship:

Zaandam

Itinerary:

San Diego to Vancouver

Select

September 29

From

$6,839

$/Day:

$134

Duration:

51 Nights

Region:

Hawaii

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

October 4

From

$1,704

$/Day:

$122

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 9

From

$2,120

$/Day:

$125

Duration:

17 Nights

Region:

Panama Canal

Depart:

San Diego

Arrive:

Ft. Lauderdale

Ship:

Eurodam

Itinerary:

San Diego to Ft. Lauderdale

Select

October 11

From

$1,346

$/Day:

$96

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 11

From

$794

$/Day:

$113

Duration:

7 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 18

From

$1,639

$/Day:

$117

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 18

From

$734

$/Day:

$105

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 21

From

$509

$/Day:

$127

Duration:

4 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

San Diego

Ship:

Koningsdam

Itinerary:

San Diego Round Trip

Select

October 25

From

$1,382

$/Day:

$99

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

October 25

From

$734

$/Day:

$105

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 1

From

$2,004

$/Day:

$118

Duration:

17 Nights

Region:

Panama Canal

Depart:

San Diego

Arrive:

Ft. Lauderdale

Ship:

Koningsdam

Itinerary:

San Diego to Ft. Lauderdale

Select

November 1

From

$1,376

$/Day:

$98

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 1

From

$834

$/Day:

$119

Duration:

7 Nights

Region:

Pacific Coast

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 8

From

$1,280

$/Day:

$91

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 8

From

$784

$/Day:

$112

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 15

From

$1,390

$/Day:

$99

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 15

From

$784

$/Day:

$112

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 19

From

$2,504

$/Day:

$86

Duration:

29 Nights

Region:

Hawaii

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

November 19

From

$1,739

$/Day:

$102

Duration:

17 Nights

Region:

Hawaii

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

November 22

From

$924

$/Day:

$132

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

November 29

From

$1,099

$/Day:

$110

Duration:

10 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

December 6

From

$1,019

$/Day:

$85

Duration:

12 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

December 6

From

$2,784

$/Day:

$96

Duration:

29 Nights

Region:

Hawaii

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

December 9

From

$1,134

$/Day:

$103

Duration:

11 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

December 18

From

$2,039

$/Day:

$120

Duration:

17 Nights

Region:

Hawaii

Depart:

San Diego

Arrive:

San Diego

Ship:

Zaandam

Itinerary:

San Diego Round Trip

Select

December 20

From

$2,241

$/Day:

$160

Duration:

14 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

December 20

From

$1,089

$/Day:

$156

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select

December 27

From

$1,244

$/Day:

$178

Duration:

7 Nights

Region:

Mexico

Depart:

San Diego

Arrive:

San Diego

Ship:

Nieuw Amsterdam

Itinerary:

San Diego Round Trip

Select